FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules
نویسندگان
چکیده
منابع مشابه
Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules.
The class II-associated invariant chain peptide (CLIP) region of invariant chain (Ii) is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site. The role of the CLIP sequence was investigated by using mutant Ii molecules with altered affinity for the DR1 peptide-binding site. Both high- ...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2019
ISSN: 1460-2377
DOI: 10.1093/intimm/dxz010